Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Encephalopathy
ADR ID BADD_A01462
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.001      Encephalopathy
Description A disorder characterized by a pathologic process involving the brain. [CTCAE] Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. [MeSH]
MedDRA Code 10014625
MeSH ID D001927
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Encephalopathy | Encephalopathy acute | Encephalopathy chronic | Encephalopathy NOS | Encephalopathy, unspecified | Influenza encephalopathy | Brain Diseases | Brain Disease | Brain Disorders | Brain Disorder | Intracranial CNS Disorders | Central Nervous System Intracranial Disorders | CNS Disorders, Intracranial | CNS Disorder, Intracranial | Intracranial CNS Disorder | Encephalon Diseases | Encephalon Disease | Intracranial Central Nervous System Disorders | Central Nervous System Disorders, Intracranial | Encephalopathies
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
Gamma-aminobutyric acid receptor subunit beta-1P15431Not Available
TransketolaseP29401T67754
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01401Metformin0.000795%
BADD_D01405Methadone0.007900%
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01425Methyldopa0.004706%
BADD_D01431Methylphenidate--
BADD_D01435Methylprednisolone hemisuccinate0.041967%
BADD_D01442Metoclopramide--
BADD_D01445Metoprolol--
BADD_D01449Metronidazole0.004638%
BADD_D01455Micafungin--
BADD_D01456Micafungin sodium--
BADD_D01470Minocycline0.000518%
BADD_D01479Mitotane--
BADD_D01498Morphine--
BADD_D01506Muromonab-cd3--
BADD_D01507Mycophenolate mofetil0.010462%
BADD_D01508Mycophenolic acid0.001737%
BADD_D01525Naloxone--
BADD_D01526Naloxone hydrochloride--
BADD_D01549Nelarabine--
BADD_D01567Nilotinib--
BADD_D01572Nitisinone--
BADD_D01599Olanzapine0.007575%
BADD_D01614Omeprazole--
BADD_D01617Ondansetron0.000100%
BADD_D01624Orlistat0.038880%
BADD_D01627Oseltamivir0.000578%
BADD_D01633Oxaliplatin0.002398%
BADD_D01637Oxcarbazepine0.002493%
The 6th Page    First    Pre   6 7 8 9    Next   Last    Total 9 Pages